July 2015

This is a talk I gave May 24th 2015 at the BCCFP Family Medicine Conference.

I discuss all the evidence I could find around the benefits and harms of metformin. Metformin is considered the gold standard medication for type 2 diabetes and for many years I said as much. However if one looks in detail at the evidence one quickly finds that while it does lower glucose, the evidence that it reduces the risk for cardiovascular disease and other outcomes is pretty minimal at best.

Fortunately the risk that it causes serious side effects like lactic acidosis is also probably close to, if not zero, if not taken in overdose. If you think I have misrepresented the best available evidence or if I missed evidence please let me know.

I have no personal issues with metformin or even other treatments for type 2 diabetes, I just want people to be aware of the best available evidence when they make decisions.